Also on Longevity Health Lens Podcast
Hosted by Dr. Adrian Laurence, a New Zealand lifestyle medicine doctor and longevity expert, this podcast helps you live longer, feel better, and perform at your best — without extremes, fads, or false promises.
Each episode explores the science of aging, metabolism, hormones, exercise, sleep, and nutrition through an evidence-based, real-world lens.
Learn practical strategies to boost energy, sharpen focus, and build lasting health after 35.
Episodes

Mar 18, 2026
Mar 18, 2026
7 min
Get free weekly science-backed tips to feel better, live longer 👉 https://dradrianlaurence.substack.com/welcomeThe Hidden Cost of Morning Fasting + High Caffeine After 40: Cortisol, Fatigue, and Metabolic StressFamily and lifestyle medicine doctor Adrian describes a common pattern he sees in patients—skipping food until midday while using high-dose morning caffeine to push through extended fasting—and explains how it can backfire, especially for people over 40 with stress or sleep issues. He outlines how caffeine taken during the natural cortisol awakening response can keep cortisol elevated into the afternoon and evening, driving energy crashes, more caffeine use, disrupted sleep architecture, and a self-reinforcing cycle of fatigue, anxiety, irritability, poor exercise recovery, and metabolic dysfunction. He notes that time-restricted eating and intermittent fasting can help in some contexts but are not universal, highlighting caffeine’s long half-life, circadian misalignment from skipping morning meals, and HPA-axis effects on insulin sensitivity and central adiposity. He suggests a “clinical reset” with morning protein, light exposure, gentle movement, and moderating caffeine while reassessing aggressive fasting.00:00 Wellness Pattern Warning00:35 Fasting Plus Caffeine Trap01:06 Cortisol Cycle Explained02:14 Crash And Sleep Spiral03:10 When Fasting Helps Or Hurts03:37 What Research Actually Says05:01 Circadian Clocks And Meals05:44 Signs It’s Not Working06:12 Clinical Reset Protocol07:01 Listen To Your Body**This video is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this content. Dr. Adrian Laurence provides general health information and does not establish a doctor–patient relationship through this video or any related content.**Instagram: /dradrianlaurenceThreads: https://www.threads.com/@dradrianlaurence Facebook: https://www.facebook.com/profile.php?id=61572349556437

Mar 17, 2026
Mar 17, 2026
6 min
Get free weekly science-backed tips to feel better, live longer 👉 https://dradrianlaurence.substack.com/welcomeWhy Dieting & Cardio Don’t Fix Visceral Fat (and What Does)Family and lifestyle medicine doctor Adrian explains that people can lose weight yet retain visceral fat, the metabolically active fat around abdominal organs that drives inflammation and disease risk. Visceral fat secretes pro-inflammatory cytokines (TNF-alpha, IL-6), lowers adiponectin, impairs liver lipid metabolism, and is strongly linked to cardiovascular and metabolic disease, liver disease, cognitive decline, and mortality. He argues calorie restriction and steady-state cardio often reduce scale weight without effectively targeting visceral fat, which can remain high despite months of effort. Key mechanisms for reducing visceral fat include building skeletal muscle through consistent progressive resistance training (2–4 sessions/week), improving post-meal glucose control with 10–15 minutes of light walking, and prioritizing adequate protein for satiety and insulin sensitivity. DEXA scans measure visceral fat directly, while waist measures are practical proxies.00:00 Hidden Fat Problem00:44 What Visceral Fat Does01:38 Why Diet Cardio Fail02:21 Muscle Glucose Sink03:32 Walk After Meals04:07 Protein And Tracking05:02 Practical Action Plan06:16 Long Game Wrap Up**This video is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this content. Dr. Adrian Laurence provides general health information and does not establish a doctor–patient relationship through this video or any related content.**Instagram: /dradrianlaurenceThreads: https://www.threads.com/@dradrianlaurence Facebook: https://www.facebook.com/profile.php?id=61572349556437

Mar 16, 2026
Mar 16, 2026
8 min
Get free weekly science-backed tips to feel better, live longer 👉 https://dradrianlaurence.substack.com/welcomeWhy Fitness Gets Harder After 35 (And What to Do About It)Adrian, a 47-year-old family and lifestyle medicine doctor, explains why what worked for staying lean and energized in your 20s often stops working after the mid-30s due to measurable biological changes rather than lack of discipline. He outlines three interacting shifts—hormonal changes (including testosterone decline and variable estrogen/progesterone), reduced mitochondrial function and biogenesis capacity (especially with sedentary aging), and declining insulin sensitivity with less responsive muscle protein synthesis—plus age-related declines in slow-wave sleep that affect recovery and metabolic health. He emphasizes these systems are responsive to intervention and recommends optimizing for your current age by prioritizing consistent progressive resistance training to build and preserve muscle, improving sleep quality, increasing and better concentrating protein per meal (including higher leucine needs), and adapting exercise stimulus and recovery to maintain a healthier biological trajectory.00:00 Why Your Body Changes00:48 Three Systems Shift02:35 How the Shifts Compound03:24 What Research Shows05:08 Sleep and Protein Changes05:36 Interventions Still Work05:56 New Mindset After 3506:12 Muscle as the Key Lever06:41 Sleep Protein and Training Upgrades07:52 Biological Age Is Malleable08:12 Closing Thanks**This video is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this content. Dr. Adrian Laurence provides general health information and does not establish a doctor–patient relationship through this video or any related content.**Instagram: /dradrianlaurenceThreads: https://www.threads.com/@dradrianlaurence Facebook: https://www.facebook.com/profile.php?id=61572349556437

Nov 26, 2025
Nov 26, 2025
11 min
Get free weekly science-backed tips to feel better, live longer 👉 https://dradrianlaurence.substack.com/welcome5 Essential Supplements for Healthy Aging: Dr. Adrian Lawrence ExplainsIn this video, Dr. Adrian Lawrence, an accredited lifestyle medicine and family doctor, reveals five supplements that target the root causes of aging: creatine, omega-3 fatty acids, magnesium, vitamin D, and multivitamins. These supplements help preserve cognitive function, maintain muscle mass, and prevent metabolic disease by addressing specific biological mechanisms like cellular energy production, inflammation, oxidative stress, hormone decline, and cognitive deterioration. Dr. Lawrence discusses the benefits, proper dosing, and safety considerations for each supplement, emphasizing the importance of combining supplementation with real food, physical activity, quality sleep, and stress management for optimal health and disease prevention.00:00 Introduction to Aging and Supplements01:09 Understanding Creatine: Beyond Bodybuilding03:46 Omega-3 Fatty Acids: The Inflammation Fighters06:33 Magnesium: The Essential Mineral08:42 Vitamin D: The Hormone Precursor10:25 Multivitamins: Foundational Support11:05 Conclusion: Integrating Supplements for Healthy Aging**This video is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this content. Dr. Adrian Laurence provides general health information and does not establish a doctor–patient relationship through this video or any related content.**Instagram: /dradrianlaurenceThreads: https://www.threads.com/@dradrianlaurence Facebook: https://www.facebook.com/profile.php?id=61572349556437

Nov 19, 2025
Nov 19, 2025
11 min
Get free weekly science-backed tips to feel better, live longer 👉 https://dradrianlaurence.substack.com/welcomeLower Your Blood Pressure Naturally: Proven Lifestyle InterventionsIn this video, Dr. Adrian Laurence, an accredited lifestyle medicine and family doctor with over 17 years of experience, explains how lifestyle changes can effectively lower blood pressure, matching or even exceeding the effects of medication. He highlights three evidence-based intervention categories: aerobic, resistance, and isometric exercises, and discusses their benefits. Additionally, Dr. Lawrence covers the importance of dietary patterns, such as the DASH and Mediterranean diets, in managing blood pressure through natural mineral balance and nutrient-rich foods. He emphasizes the role of stress management, adequate sleep, and behavioral support in maintaining these lifestyle changes. Together with your doctor, these strategies can help reduce cardiovascular risk and medication dependency sustainably.00:00 Introduction to Blood Pressure Management00:47 The Power of Exercise02:09 Weight Management and Blood Pressure03:32 Dietary Approaches for Blood Pressure Control04:32 The Role of Sodium and Potassium06:19 The Importance of Fiber08:52 Stress, Sleep, and Blood Pressure10:01 Adherence and Personalization10:59 Conclusion and Next Steps**This video is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this content. Dr. Adrian Laurence provides general health information and does not establish a doctor–patient relationship through this video or any related content.**Instagram: /dradrianlaurenceThreads: https://www.threads.com/@dradrianlaurence Facebook: https://www.facebook.com/profile.php?id=61572349556437

Nov 13, 2025
Nov 13, 2025
11 min
Get free weekly science-backed tips to feel better, live longer 👉 https://dradrianlaurence.substack.com/welcomeReverse Brain Aging: The Surprising Benefits of Daily WalkingIn this video, Dr. Adrian Laurence, an accredited lifestyle medicine and family doctor, reveals how daily walking can reverse brain aging. Discover the four biological mechanisms that make walking a powerful brain protective intervention. Learn how consistent moderate walking can increase hippocampal volume, improve cerebral blood flow, reduce inflammation, and enhance cognitive functions. Dr. Lawrence provides practical tips on how to incorporate walking into your routine to preserve memory, sharpen focus, and reduce dementia risk by up to 25%. No expensive supplements or complicated protocols needed—just 30 minutes of consistent walking. Start today and enjoy better brain health.00:00 Introduction: The Shrinking Brain00:24 The Power of Walking: Research Insights00:51 Understanding the Hippocampus01:56 Mechanism 1: The Fertilizer Effect02:52 Mechanism 2: Reversing Shrinkage03:47 Mechanism 3: Better Blood Flow04:42 Mechanism 4: Cooling Inflammation05:33 Real-Life Benefits of Walking07:31 Practical Walking Prescription09:16 Overcoming Barriers to Walking10:48 Conclusion: Start Walking Today**This video is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this content. Dr. Adrian Laurence provides general health information and does not establish a doctor–patient relationship through this video or any related content.**Instagram: /dradrianlaurenceThreads: https://www.threads.com/@dradrianlaurence Facebook: https://www.facebook.com/profile.php?id=61572349556437

Nov 6, 2025
Nov 6, 2025
12 min
Get free weekly science-backed tips to feel better, live longer 👉 https://dradrianlaurence.substack.com/welcomeThe Secret to Reversing Metabolic Decline After 40: What You Need to KnowIn this video, Dr. Adrian, an accredited lifestyle and family medicine doctor with over 17 years of experience, reveals why traditional advice on diet and exercise can fail to address aging and stubborn belly fat. He explains the role of 'zombie cells'—damaged cells that disrupt metabolism and accelerate aging. Dr. Adrian breaks down three scientifically-backed cellular signals to reverse metabolic decline after 40: high-intensity strength training, nutritional timing (including intermittent fasting), and optimizing recovery through quality sleep and stress management. Learn how these strategies can help you lose fat, build muscle, and boost energy without extreme diets or hours in the gym.00:00 Introduction: Why Your Efforts Aren't Working00:46 Understanding Zombie Cells01:36 Inflammation and Metabolic Problems02:39 The Role of Belly Fat and Mitochondria05:52 Exercise: The Key to Cellular Renewal07:48 Nutritional Timing for Metabolic Health09:39 Optimizing Recovery and Stress Management11:02 Recap and Final Thoughts**This video is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this content. Dr. Adrian Laurence provides general health information and does not establish a doctor–patient relationship through this video or any related content.**Instagram: /dradrianlaurenceThreads: https://www.threads.com/@dradrianlaurence Facebook: https://www.facebook.com/profile.php?id=61572349556437

Oct 31, 2025
Oct 31, 2025
7 min
Get free weekly science-backed tips to feel better, live longer 👉 https://dradrianlaurence.substack.com/welcomeThe Protein Mistake: Are You Sabotaging Your Health After 35?In this video, Dr. Adrian Laurence, a lifestyle medicine and family doctor with over 17 years of experience, addresses a common protein intake mistake made by individuals over the age of 35. He explains how the outdated Recommended Dietary Allowance (RDA) is insufficient for maintaining muscle, optimizing energy, and supporting healthy aging. Dr. Laurence introduces the concept of anabolic resistance and provides a new strategy to counteract it, recommending a higher protein intake of 1.6 to 2.0 grams per kilogram of body weight. He offers practical tips for meal planning and highlights the importance of combining this strategy with regular resistance training to protect muscle mass, boost metabolism, and ensure long-term health.00:00 The Protein Mistake Over 3501:00 Understanding Anabolic Resistance02:36 Optimizing Protein Intake04:49 Practical Protein Strategies07:28 Conclusion and Next Steps**This video is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this content. Dr. Adrian Laurence provides general health information and does not establish a doctor–patient relationship through this video or any related content.**Instagram: /dradrianlaurenceThreads: https://www.threads.com/@dradrianlaurence Facebook: https://www.facebook.com/profile.php?id=61572349556437

Oct 28, 2025
Oct 28, 2025
8 min
Get free weekly science-backed tips to feel better, live longer 👉 https://dradrianlaurence.substack.com/welcomeCreatine's Surprising Benefits for Brain Health After 40In this video, Dr. Adrian Laurence, a lifestyle medicine and family doctor, explores the emerging science of how creatine supplementation can benefit brain health, particularly in adults over 40. While creatine is commonly associated with muscle performance, new research indicates that it also acts as a crucial cognitive buffer against the energy crises faced by aging brains. The video details how creatine helps maintain cognitive function during periods of metabolic stress, including sleep deprivation, work pressures, and emotional stress. Dr. Lawrence also provides practical dosing advice and addresses common concerns about kidney health. Join him to learn how creatine can serve as crucial 'brain insurance' in our demanding modern lives.00:00 Introduction to Creatine and Brain Health00:23 The Brain's Energy Crisis After 4000:55 How Creatine Supports Cognitive Function02:05 Research on Creatine's Cognitive Benefits04:37 Practical Dosing Recommendations06:35 Addressing Common Concerns and Misconceptions07:22 Who Benefits Most from Creatine?07:52 Conclusion and Next Steps**This video is for informational and educational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have seen or heard in this content. Dr. Adrian Laurence provides general health information and does not establish a doctor–patient relationship through this video or any related content.**Instagram: /dradrianlaurenceThreads: https://www.threads.com/@dradrianlaurence Facebook: https://www.facebook.com/profile.php?id=61572349556437

Oct 26, 2025




